Heart Rhythm
Volume 7, Issue 4 , Pages 520-528 , April 2010

n-3 Polyunsaturated fatty acids alter expression of fibrotic and hypertrophic genes in a dog model of atrial cardiomyopathy

  • Andrew Ramadeen, BSc

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
    • Cardiovascular Sciences Collaborative Program, University of Toronto, Toronto, Ontario, Canada
  • ,
  • Gabriel Laurent, MD, PhD

      Affiliations

    • Department of Cardiology, University Hospital BOCAGE, Dijon, France
  • ,
  • Claudia C. dos Santos, MD, MSc

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Xudong Hu, MD

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
    • Division of Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada
  • ,
  • Kim A. Connelly, MD, PhD

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Medicine, St. Vincent's Hospital, University of Melbourne, Victoria, Australia
  • ,
  • Bruce J. Holub, PhD

      Affiliations

    • Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
  • ,
  • Iqwal Mangat, MD, FHRS

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
    • Division of Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  • ,
  • Paul Dorian, MD, MSc, FHRS

      Affiliations

    • Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada
    • Cardiovascular Sciences Collaborative Program, University of Toronto, Toronto, Ontario, Canada
    • Division of Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada
    • Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Paul Dorian, St. Michael's Hospital, Division of Cardiology, 30 Bond Street, 6-050Q, Toronto, ON M5B 1W8, Canada

Received 14 September 2009 ,Accepted 15 December 2009.

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 This work was supported by The Heart and Stroke Foundation of Ontario, St. Michael's Hospital; the Li Ka Shing Knowledge Institute; a Tailored Advance Collaborative Training in Cardiovascular Sciences (TACTICS) scholarship (Canada) to Dr. Connelly; and a National Health and Medical Research Council of Australia Neil Hamilton Fairley scholarship (440712) to Dr. Connelly.

PII: S1547-5271(09)01417-9

doi: 10.1016/j.hrthm.2009.12.016

Heart Rhythm
Volume 7, Issue 4 , Pages 520-528 , April 2010