Heart Rhythm
Volume 2, Issue 11 , Pages 1250-1252 , November 2005

Electrocardiographic imaging (ECGI), a novel diagnostic modality used for mapping of focal left ventricular tachycardia in a young athlete

  • Anselma Intini, MD

      Affiliations

    • Department of Medicine (Cardiology), Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Robert N. Goldstein, MD

      Affiliations

    • Department of Medicine (Cardiology), Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Ping Jia, PhD

      Affiliations

    • Department of Biomedical Engineering, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • Authors Ping Jia and Charulatha Ramanathan are employees and stockholders of CardioInsight, Inc., a company that plans to commercialize electrocardiographic imaging as a clinical tool
    • ,
  • Charulatha Ramanathan, PhD

      Affiliations

    • Department of Biomedical Engineering, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • Authors Ping Jia and Charulatha Ramanathan are employees and stockholders of CardioInsight, Inc., a company that plans to commercialize electrocardiographic imaging as a clinical tool
    • ,
  • Kyungmoo Ryu, PhD

      Affiliations

    • Department of Biomedical Engineering, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Bartolomeo Giannattasio, MD, PhD

      Affiliations

    • Department of Medicine (Cardiology), Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Robert Gilkeson, MD

      Affiliations

    • Department of Radiology, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Bruce S. Stambler, MD

      Affiliations

    • Department of Medicine (Cardiology), Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • ,
  • Pedro Brugada, MD

      Affiliations

    • Cardiovascular Center Aalst/OLV Hospital, Aalst, Belgium
    • ,
  • William G. Stevenson, MD

      Affiliations

    • Department of Medicine (Cardiology) Brigham and Women’s Hospital, Boston, Massachusetts
    • ,
  • Yoram Rudy, PhD

      Affiliations

    • Department of Biomedical Engineering, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • Present affiliation: Cardiac Bioelectricity and Arrhythmia Center, Washington University in St. Louis, St. Louis, Missouri
    • ,
  • Albert L. Waldo, MD

      Affiliations

    • Department of Medicine (Cardiology), Case Western Reserve University/University Hospitals of Cleveland, Cleveland, Ohio
    • Corresponding Author InformationAddress reprint requests and correspondence: Albert L Waldo, MD, Division of Cardiology, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, Ohio 44106

Received 26 May 2005 ,Accepted 17 August 2005.

References 

  1. Ramanathan C , Ghanem RN , Jia P , Ryu K , Rudy Y . Noninvasive electrocardiographic imaging for cardiac electrophysiology and arrhythmia . Nat Med . 2004;10:422–428
  2. Rudy Y , Burnes JE . Noninvasive electrocardiographic imaging (ECGI) . Ann Noninvas Electrocardiol . 1999;4:340–359
  3. Taccardi B , Punske B . Body surface potential mapping . In:  Zipes DP ,  Jalife J editor. Cardiac electrophysiology (from cell to bedside) . Philadelphia: WB Saunders; 2004;p. 803–811
  4. Gulrajani RM . The forward and inverse problems of Electrocardiography . IEEE Eng Med Biol Mag . 1998;17:84–101
  5. Oster HS , Taccardi B , Lux RL , Ershler PR , Rudy Y . Noninvasive electrocardiographic imaging (reconstruction of epicardial potentials, electrograms, and isochrones and localization of single and multiple electrocardic events) . Circulation . 1997;96:1012–1024
  6. Oster HS , Taccardi B , Lux RL , Ershler PR , Rudy Y . Electrocardiographic imaging (noninvasive characterization of intramural myocardial activation from inverse-reconstructed epicardial potentials and electrograms) . Circulation . 1998;97:1496–1507
  7. Burnes JE , Taccardi B , MacLeod RS , Rudy Y . Noninvasive ECG imaging of electrophysiologically abnormal substrates in infarcted hearts (a model study) . Circulation . 2000;101:533–540
  8. Burnes JE , Taccardi B , Rudy Y . A noninvasive imaging modality for cardiac arrhythmias . Circulation . 2000;102:2152–2158
  9. Ramanathan C , Rudy Y . Electrocardiographic imaging. II. Effect of torso inhomogeneities on the noninvasive reconstruction of epicardial potentials, electrograms and isochrones . J Cardiovasc Electrophysiol . 2001;12:241–252
  10. Ghanem RN , Burnes JE , Waldo AL , Rudy Y . Imaging dispersion of myocardial repolarization. II. Noninvasive reconstruction of epicardial measures . Circulation . 2001;104:1306–1312
  11. Burnes JE , Taccardi B , Ershler P , Rudy Y . Noninvasive ECG imaging of substrate and intramural ventricular tachycardia in infarcted hearts . J Am College Cardiol . 2001;38:2071–2207
  12. Ghanem RN , Jia P , Ramanathan C , Ryu K , Markowitz A , Rudy Y . Noninvasive electrocardiographic imaging (ECGI) (comparison to intraoperative mapping in patients) . Heart Rhythm . 2005;2:339–354
  13. Ghosh S , Rudy Y . Accuracy of quadratic versus linear interpolation in noninvasive electrocardiographic imaging (ECGI) . Ann Biomed Eng . 2005;33:1187–1201

 The other authors have no conflict of interest to disclose.EDITOR’S NOTE: Although case reports are limited to four authors, we made an exception in this case because of its complexity and the need for collaboration among multiple experts.

PII: S1547-5271(05)02011-4

doi: 10.1016/j.hrthm.2005.08.019

Heart Rhythm
Volume 2, Issue 11 , Pages 1250-1252 , November 2005

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