Heart Rhythm
Volume 3, Issue 10 , Pages 1140-1147 , October 2006

Nonexcitatory, cardiac contractility modulation electrical impulses: Feasibility study for advanced heart failure in patients with normal QRS duration

  • Suresh B. Neelagaru, MD

      Affiliations

    • Lone Star Arrhythmia and Heart Failure Center, Amarillo, Texas
    • ,
  • Javier E. Sanchez, MD

      Affiliations

    • Texas Cardiac Arrhythmia, Austin, Texas
    • ,
  • Stanley K. Lau, MD

      Affiliations

    • Southern California Heart Centers, San Gabriel, California
    • ,
  • Steven M. Greenberg, MD

      Affiliations

    • St. Francis Hospital, Roslyn, New York
    • ,
  • Nirav Y. Raval, MD

      Affiliations

    • St. Joseph’s Hospital, Atlanta, Georgia
    • ,
  • Seth Worley, MD

      Affiliations

    • Lancaster General Hospital, Lancaster, Pennsylvania
    • ,
  • Jill Kalman, MD

      Affiliations

    • New York University School of Medicine, New York, New York
    • ,
  • Andrew D. Merliss, MD

      Affiliations

    • BryanLGH Medical Center, Lincoln, Nebraska
    • ,
  • Steven Krueger, MD

      Affiliations

    • BryanLGH Medical Center, Lincoln, Nebraska
    • ,
  • Mark Wood, MD

      Affiliations

    • Virginia Commonwealth University Medical Center, Richmond, Virginia
    • ,
  • Marc Wish, MD

      Affiliations

    • Arrhythmia Associates, Fairfax, Virginia
    • ,
  • Daniel Burkhoff, MD

      Affiliations

    • Cardiovascular Research Foundation, Orangeburg, New York
    • Columbia University, New York, New York
    • ,
  • Koonlawee Nademanee, MD

      Affiliations

    • Pacific Rim EP, Inglewood, California
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Koonlawee Nademanee, Pacific Rim Electrophysiology Research Institute, 575 E. Hardy Street, Suite 201, Inglewood, California 90301.

Received 27 April 2006 ,Accepted 26 June 2006.

References 

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  5. St. John Sutton MG, Plappert T, Abraham WT, Smith AL, DeLurgio DB, Leon AR, et al. Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure . Circulation . 2003;107:1985–1990
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  11. Pappone C, Augello G, Rosanio S, Vicedomini G, Santinelli V, Romano M, et al. First human chronic experience with cardiac contractility modulation by nonexcitatory electrical currents for treating systolic heart failure: mid-term safety and efficacy results from a multicenter study . J Cardiovasc Electrophysiol . 2004;15:418–427
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 This study was supported by a research grant from IMPULSE Dynamics, Orangeburg, New York, USA, the manufacturer of the OPTIMIZER system. Dr. Burkhoff is an employee of IMPULSE Dynamics.

PII: S1547-5271(06)01727-9

doi: 10.1016/j.hrthm.2006.06.031

Heart Rhythm
Volume 3, Issue 10 , Pages 1140-1147 , October 2006

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