Heart Rhythm
Volume 3, Issue 12 , Pages 1469-1480 , December 2006

KCNE2 is colocalized with KCNQ1 and KCNE1 in cardiac myocytes and may function as a negative modulator of IKs current amplitude in the heart

  • Dong-Mei Wu, PhD

      Affiliations

    • Department of Physiology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Min Jiang, PhD

      Affiliations

    • Department of Physiology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Mei Zhang, PhD

      Affiliations

    • Department of Physiology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Xian-Sheng Liu, MD

      Affiliations

    • Department of Physiology, Virginia Commonwealth University, Richmond, Virginia
    • ,
  • Yuliya V. Korolkova, PhD

      Affiliations

    • Shemiyakin-Ovchinnikov Institute of Biological Chemistry, Russian Academy of Sciences, Moscow, Russia.
    • ,
  • Gea-Ny Tseng, PhD

      Affiliations

    • Department of Physiology, Virginia Commonwealth University, Richmond, Virginia
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Gea-Ny Tseng, Department of Physiology, Virginia Commonwealth University, 1101 East Marshall Street, Richmond, Virginia 23298.

Received 1 June 2006 ,Accepted 14 August 2006.

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 This study was supported by Grants RO1-HL-46451 and HL-67840 from the National Heart, Lung, and Blood Institute of the National Institutes of Health to Dr. Tseng. The authors thank Dr. Jurgen Punter from Aventis Pharma Deutschland GmbH for the generous gift of HMR1556.

PII: S1547-5271(06)01929-1

doi: 10.1016/j.hrthm.2006.08.019

Heart Rhythm
Volume 3, Issue 12 , Pages 1469-1480 , December 2006

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