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Heart Rhythm
Volume 6, Issue 3,
Supplement
, Pages S36-S44
, March 2009
Evidence regarding clinical use of microvolt T-wave alternans
References
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- T-wave alternans as a predictor for sudden cardiac death after myocardial infarction. Am J Cardiol. 2002;89:79–82
- Onset heart rate of microvolt-level T-wave alternans provides clinical and prognostic value in nonischemic dilated cardiomyopathy. J Am Coll Cardiol. 2002;39:295–300
- T-wave alternans negative coronary patients with low ejection and benefit from defibrillator implantation. Lancet. 2003;362:125–126
- Microvolt T-wave alternans and the risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol. 2006;47:456–463
- Predictive value of microvolt T-wave alternans for sudden cardiac death in patients with preserved cardiac function after acute myocardial infarction: results of a collaborative cohort study. J Am Coll Cardiol. 2006;48:2268–2274
- Prognostic value of T-wave alternans in patients with heart failure due to nonischemic cardiomyopathy: results of the ALPHA Study. J Am Coll Cardiol. 2007;50:1896–1904
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- Prognostic utility of microvolt T-wave alternans in risk stratification of patients with ischemic cardiomyopathy. J Am Coll Cardiol. 2006;47:1820–1827
- Late-breaking clinical trials abstract: primary results from the Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients (MASTER I) trial. Circulation. 2007;116:2631
- Late-breaking clinical trials abstract: the Alternans Before Cardioverter Defibrillator (ABCD) trial: a noninvasive strategy for primary prevention of sudden cardiac death using T-wave alternans. Circulation. 2006;114:2426
- T-wave alternans SCD HeFT study: primary end point analysis. Circulation. 2006;114:II_428–II_429(abstr 2113)
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- Microvolt T-wave alternans distinguishes between patients likely and patients not likely to benefit from implanted cardiac defibrillator therapy: a solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II conundrum. Circulation. 2004;110:1885–1889
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- Effect of long-term beta-blocker therapy on microvolt-level T-wave alternans in association with the improvement of the cardiac sympathetic nervous system and systolic function in patients with non-ischemic heart disease. Circ J. 2003;67:821–825
- The frequency and incremental cost of major complications among Medicare beneficiaries receiving implantable cardioverter-defibrillators. J Am Coll Cardiol. 2006;47:2493–2497
- Complications of implantable cardioverter defibrillator therapy in 440 consecutive patients. Pacing Clin Electrophysiol. 2005;28:926–932
- Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med. 2004;351:2481–2488
- Microvolt T-wave alternans identifies patients with ischemic cardiomyopathy who benefit from implantable cardioverter-defibrillator therapy. J Am Coll Cardiol. 2007;49:50–58
- Heart disease and stroke statistics—2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007;115:e69–e171
- Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation. 2005;112:3738–3744
- Noninvasive risk assessment early after a myocardial infarction. J Am Coll Cardiol. 2007;50:2275–2284
- Population-based analysis of sudden cardiac death with and without left ventricular systolic dysfunction: two-year findings from the Oregon Sudden Unexpected Death Study. J Am Coll Cardiol. 2006;47:1161–1166
- “Indeterminate” microvolt T-wave alternans tests predict high risk of death or sustained ventricular arrhythmias in patients with left ventricular dysfunction. J Am Coll Cardiol. 2006;48:1399–1404
- Long-term clinical course of patients after termination of ventricular tachyarrhythmia by an implanted defibrillator. Circulation. 2004;110:3760–3765
Dr. Hohnloser has research grant, consultancy, and speaker's bureau associations with St. Jude Medical and Sanofi Aventis. The MTWA technology was developed in Dr. Cohen's laboratory at the Massachusetts Institute of Technology (MIT). MIT licensed the technology to Cambridge Heart, Inc. Dr. Cohen has a financial involvement with Cambridge Heart as a consequence of the original licensure of the technology and his ongoing service as a consultant, director, and speaker's bureau member. Dr. Cohen has been a consultant to Medtronic, Inc. Dr Takanori Ikeda has no conflict of interest.
PII: S1547-5271(08)00978-8
doi: 10.1016/j.hrthm.2008.10.011
© 2009 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
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Heart Rhythm
Volume 6, Issue 3,
Supplement
, Pages S36-S44
, March 2009
