Heart Rhythm
Volume 6, Issue 2 , Pages 187-188 , February 2009

Sex discrimination and the QT interval

  • Ronald D. Berger, MD, PhD, FHRS

      Affiliations

    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Ronald D. Berger, Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Carnegie 592, Baltimore, Maryland 21287

References 

  1. Tomaselli GF, Beuckelmann DJ, Calkins HG, et al. Sudden cardiac death in heart failure (The role of abnormal repolarization). Circulation. 1994;90:2534–2539
  2. Haigney MC, Zareba W, Nasir JM, et al. Gender differences and risk of ventricular tachycardia or ventricular fibrillation. Heart Rhythm. 2009;6:180–186
  3. Berger RD, Kasper EK, Baughman KL, et al. Beat-to-beat QT interval variability: novel evidence for repolarization lability in ischemic and nonischemic dilated cardiomyopathy. Circulation. 1997;96:1557–1565
  4. Haigney MC, Zareba W, Gentlesk PJ, et al. QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients. J Am Coll Cardiol. 2004;44:1481–1487
  5. Pham TV, Rosen MR. Sex, hormones, and repolarization. Cardiovasc Res. 2002;53:740–751
  6. Weiss JN, Garfinkel A, Karagueuzian HS, et al. Chaos and the transition to ventricular fibrillation: a new approach to antiarrhythmic drug evaluation. Circulation. 1999;99:2819–2826
  7. Wasserstrom JA, Kapur S, Jones S, et al. Characteristics of intracellular Ca2+ cycling in intact rat heart: a comparison of sex differences. Am J Physiol Heart Circ Physiol. 2008;295:H1895–H1904
  8. Nakagawa M, Ooie T, Ou B, et al. Gender differences in autonomic modulation of ventricular repolarization in humans. J Cardiovasc Electrophysiol. 2005;16:278–284
  9. Yeragani VK, Pohl R, Jampala VC, et al. Effect of posture and isoproterenol on beat-to-beat heart rate and QT variability. Neuropsychobiology. 2000;41:113–123
  10. Baumert M, Lambert GW, Dawood T, et al. QT interval variability and cardiac norepinephrine spillover in patients with depression and panic disorder. Am J Physiol Heart Circ Physiol. 2008;295:H962–H968
  11. Chow T, Kereiakes DJ, Onufer J, et al. Does microvolt T-wave alternans testing predict ventricular tachyarrhythmias in patients with ischemic cardiomyopathy and prophylactic defibrillators? (The MASTER (Microvolt T Wave Alternans Testing for Risk Stratification of Post-Myocardial Infarction Patients) trial). J Am Coll Cardiol. 2008;52:1607–1615
  12. Gold MR, Ip JH, Costantini O, et al. Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy. Circulation. 2008;118:2022–2028
  13. Piccirillo G, Magri D, Matera S, et al. F. QT variability strongly predicts sudden cardiac death in asymptomatic subjects with mild or moderate left ventricular systolic dysfunction: a prospective study. Eur Heart J. 2007;28:1344–1350

PII: S1547-5271(08)01186-7

doi: 10.1016/j.hrthm.2008.11.031

Heart Rhythm
Volume 6, Issue 2 , Pages 187-188 , February 2009

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