Heart Rhythm
Volume 6, Issue 5 , Pages 634-641, May 2009

Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae

  • J. Gustav Smith, MD

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts
    • Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts
    • ,
  • Jennifer K. Lowe, PhD

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts
    • ,
  • Sirisha Kovvali, BA

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • ,
  • Julian B. Maller, BSc

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts
    • Department of Statistics, University of Oxford, Oxford, United Kingdom
    • ,
  • Jacqueline Salit, MS

      Affiliations

    • Laboratory of Molecular Genetics, Rockefeller University, New York, New York
    • ,
  • Mark J. Daly, PhD

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts
    • ,
  • Markus Stoffel, MD, PhD

      Affiliations

    • Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland
    • ,
  • David M. Altshuler, MD, PhD

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts
    • Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts
    • ,
  • Jeffrey M. Friedman, MD, PhD

      Affiliations

    • Laboratory of Molecular Genetics, Rockefeller University, New York, New York
    • ,
  • Jan L. Breslow, MD

      Affiliations

    • Laboratory of Biochemical Genetics and Metabolism, New York, New York
    • ,
  • Christopher Newton-Cheh, MD, MPH

      Affiliations

    • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge
    • Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts
    • Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts
    • Corresponding Author InformationAddress reprint requests and correspondence: Christopher Newton-Cheh, M.D., M.P.H., Center for Human Genetic Research, Cardiovascular Research Center, Massachusetts General Hospital, 185 Cambridge Street, CPZN 5.242, Boston, Massachusetts 02114

Received 12 January 2009; accepted 11 February 2009. published online 17 February 2009.

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 Dr. Newton-Cheh was supported by National Institutes of Health grant no. NIH K23-HL-080025, a Doris Duke Charitable Foundation Clinical Scientist Development Award, and a Burroughs Wellcome Fund Career Award for Medical Scientists. J.K. Lowe was supported by a Tosteson Post-Doctoral Fellowship for Basic Research from the Massachusetts Biomedical Research Corporation. Dr. Altshuler is a Burroughs Wellcome Fund Clinical Scholar in Translational Research and a Distinguished Clinical Scholar of the Doris Duke Charitable Foundation. The genome-wide association scan on Kosrae was supported by grants from the Starr Foundation and Howard Hughes Medical Institute.

PII: S1547-5271(09)00171-4

doi:10.1016/j.hrthm.2009.02.022

Heart Rhythm
Volume 6, Issue 5 , Pages 634-641, May 2009

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