Heart Rhythm
Volume 6, Issue 6 , Pages 742-748 , June 2009

Temporary leadless pacing in heart failure patients with ultrasound-mediated stimulation energy and effects on the acoustic window

  • Kathy L. Lee, MBBS

      Affiliations

    • Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Kathy L. Lee, Cardiology Division, Department of Medicine, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
    • ,
  • Hung-Fat Tse, MD, PhD

      Affiliations

    • Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China
    • ,
  • Debra S. Echt, MD, FHRS

      Affiliations

    • EBR Systems, Inc., Sunnyvale, California
    • ,
  • Chu-Pak Lau, MD, FHRS

      Affiliations

    • Cardiology Division, Department of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China

Received 22 January 2008 ,Accepted 18 February 2009.

References 

  1. Auricchio A, Abraham WT. Cardiac resynchronization therapy: current state of the art. Circulation. 2004;109:300–307
  2. Cleland JGF, Daubert J, Erdmann E, et al. CARE-HF study investigators The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1–11
  3. Bristow MR, Saxon LA, Boehmer J, et al. COMPANION investigators Cardiac resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350:2140–2150
  4. Sutton MGSJ, Plappert T, Abraham WT, et al. Multicenter InSync Randomized Clinical Evaluation (MIRACLE) study group Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure. Circulation. 2003;107:1985–1990
  5. Abraham WT, Young JB, Leon AR, et al. Multicenter InSync ICD II study group Effects of cardiac resynchronization on disease progression in patients with left ventricular systolic dysfunction, an indication for an implantable cardioverter-defibrillator, and mildly symptomatic chronic heart failure. Circulation. 2004;110:2864–2868
  6. Stevenson LW. The points for pacing. J Am Coll Cardiol. 2003;42:1460–1462
  7. Saxon LA, Ellenbogen KA. Resynchronization therapy for the treatment of heart failure. Circulation. 2003;108:1044–1048
  8. Pires LA, Abraham WT, Young JB, et al. MIRACLE and MIRACLE-ICD investigators Clinical predictors and timing of New York Heart Association class improvement with cardiac resynchronization therapy in patients with advanced chronic heart failure: results from the Multicenter InSync Randomized Clinical Evaluation (MIRACLE) and Multicenter InSync ICD Randomized Clinical Evaluation (MIRACLE-ICD) trials. Heart J. 2006;151:837–843
  9. Pitzalis MV, Iacoviello M, Romito R, et al. Ventricular asynchrony predicts a better outcome in patients with chronic heart failure receiving cardiac resynchronization therapy. J Am Coll Cardiol. 2005;45:65–69
  10. Lambiase PD, Rinaldi A, Hauck J, et al. Non-contact left ventricular endocardial mapping in cardiac resynchronisation therapy. Heart. 2004;90:44–51
  11. Garrigue S, Jais P, Espil G, et al. Comparison of chronic biventricular pacing between epicardial and endocardial left ventricular stimulation using Doppler tissue imaging in patients with heart failure. Am J Cardiol. 2001;88:858–862
  12. León AR, Abraham ST, Curtis AB, et al. MIRACLE study program Safety of transvenous cardiac resynchronization system implantation in patients with chronic heart failure. J Am Coll Cardiol. 2005;46:2348–2356
  13. Echt DS, Cowan MW, Riley RE, et al. Feasibility and safety of a novel technology for pacing without leads. Heart Rhythm. 2006;10:1202–1206
  14. Lee KL, Lau C-P, Tse H-F, et al. First human demonstration of cardiac stimulation with transcutaneous ultrasound energy delivery: implications for wireless pacing with implantable devices. J Am Coll Cardiol. 2007;50:877–883

 This study was supported by a research grant from EBR Systems, Inc.

 Dr. Echt is employed by EBR Systems, Inc.

PII: S1547-5271(09)00207-0

doi: 10.1016/j.hrthm.2009.02.025

Heart Rhythm
Volume 6, Issue 6 , Pages 742-748 , June 2009

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