Heart Rhythm
Volume 8, Issue 8 , Pages 1207-1213 , August 2011

Genotype-specific QT correction for heart rate and the risk of life-threatening cardiac events in adolescents with congenital long-QT syndrome

  • Alon Barsheshet, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Alon Barsheshet, Heart Research Follow-up Program, Box 653, University of Rochester Medical Center, Rochester, NY 14642
    • ,
  • Derick R. Peterson, PhD

      Affiliations

    • Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, New York
    • ,
  • Arthur J. Moss, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Peter J. Schwartz, MD

      Affiliations

    • Department of Lung, Blood, and Heart, University of Pavia, Pavia, Italy; Department of Cardiology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy; Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy; Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia
    • ,
  • Elizabeth S. Kaufman, MD

      Affiliations

    • Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio
    • ,
  • Scott McNitt, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Slava Polonsky, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Jonathan Buber, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Wojciech Zareba, MD, PhD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Jennifer L. Robinson, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Michael J. Ackerman, MD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Jesaia Benhorin, MD

      Affiliations

    • Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    • ,
  • Jeffrey A. Towbin, MD

      Affiliations

    • Department of Pediatrics, University of Cincinnati Children's Hospital, Cincinnati, Ohio
    • ,
  • G. Michael Vincent, MD

      Affiliations

    • LDS Hospital, Salt Lake City, Utah
    • ,
  • Li Zhang, MD

      Affiliations

    • LDS Hospital, Salt Lake City, Utah
    • ,
  • Ilan Goldenberg, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York

Received 11 November 2010 ,Accepted 3 March 2011.

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 This work was supported in part by research grants HL-33843 and HL-51618 to the University of Rochester Medical Center from the National Institutes of Health, Bethesda, Maryland. Dr. Moss reports receiving a research grant from GeneDx; Dr. Kaufman received research grants from CardioDx and St. Jude Medical. Dr. Ackerman has a consulting relationship and license agreement/royalty arrangement with PGxHealth and received consultant fees from Medtronic, Biotronik, Boston Scientific, and St Jude Medical. This research was carried out while Dr. Alon Barsheshet was a Mirowski-Moss Career Development Awardee at the University of Rochester Medical Center, Rochester, New York.

PII: S1547-5271(11)00276-1

doi: 10.1016/j.hrthm.2011.03.009

Heart Rhythm
Volume 8, Issue 8 , Pages 1207-1213 , August 2011

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