Heart Rhythm
Volume 8, Issue 10 , Pages 1537-1543 , October 2011

Mutation and gender-specific risk in type 2 long QT syndrome: Implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

  • Dimitry Migdalovich, BS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Arthur J. Moss, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Coeli M. Lopes, PhD

      Affiliations

    • Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, New York
    • ,
  • Jason Costa, MA

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Gregory Ouellet, MA

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Alon Barsheshet, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Scott McNitt, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Slava Polonsky, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Jennifer L. Robinson, MS

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Wojciech Zareba, MD, PhD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • ,
  • Michael J. Ackerman, MD, PhD

      Affiliations

    • Department of Pediatrics, Division of Pediatric Cardiology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Jesaia Benhorin, MD

      Affiliations

    • Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    • ,
  • Elizabeth S. Kaufman, MD

      Affiliations

    • Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio
    • ,
  • Pyotr G. Platonov, MD

      Affiliations

    • Department of Cardiology, Lund University, Lund, Sweden
    • ,
  • Wataru Shimizu, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine National Cardiovascular Center, Suita, Japan
    • ,
  • Jeffrey A. Towbin, MD

      Affiliations

    • Department of Pediatrics, University of Cincinnati Children's Hospital, Cincinnati, Ohio
    • ,
  • G. Michael Vincent, MD

      Affiliations

    • LDS Hospital, Salt Lake City, Utah
    • ,
  • Arthur A.M. Wilde, MD, PhD

      Affiliations

    • Department of Cardiology Academic Medical Center, Amsterdam, The Netherlands
    • ,
  • Ilan Goldenberg, MD

      Affiliations

    • Cardiology Division, University of Rochester Medical Center, Rochester, New York
    • Corresponding Author InformationAddress reprint requests and correspondence: Dr. Ilan Goldenberg, Heart Research Follow-Up Program, Box 653, University of Rochester Medical Center, Rochester, NY 14642

Received 9 February 2011 ,Accepted 20 March 2011.

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 Conflict of interests/disclosure: Dr. Ackerman is a consultant for Biotronik, Boston Scientific, Medtronic, PGx Health, and St. Jude Medical; and has intellectual property in PGx Health. Dr. Kaufman receives grant support from CardioDx, Cambridge Heart Inc., and St. Jude Medical. All other authors have reported that they have no relationships to disclose.

 This work was supported by research grants HL-33843 and HL-51618 from the National Institutes of Health and by a research grant from GeneDx to the Heart Research Follow-Up Program in support of the LQTS Registry.

PII: S1547-5271(11)00361-4

doi: 10.1016/j.hrthm.2011.03.049

Heart Rhythm
Volume 8, Issue 10 , Pages 1537-1543 , October 2011

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