Heart Rhythm
Volume 9, Issue 2 , Pages 275-282 , February 2012

Arrhythmia formation in subclinical (“silent”) long QT syndrome requires multiple insults: Quantitative mechanistic study using the KCNQ1 mutation Q357R as example

  • Thomas O'Hara, PhD
    • ,
  • Yoram Rudy, PhD, FHRS

      Affiliations

    • Corresponding Author InformationAddress for reprints and correspondence: Dr Yoram Rudy, PhD, Department of Biomedical Engineering, Cardiac Bioelectricity and Arrhythmia Center, Washington University in Saint Louis, Campus Box 1097, 290 Whitaker Hall, One Brookings Drive, Saint Louis, MO 63130

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 This work was supported by National Institutes of Health/National Heart, Lung, and Blood Institute grants R01-HL049054-19 and R01-HL033343-27033343-27 (to Y.R.), Fondation Leducq Award to the Alliance for CaMK Signaling in Heart Disease (to Y.R.), National Science Foundation grant CBET-0929633 (to Y.R.), and American Heart Association Predoctoral Fellowship 0815539G (to T.J.O.). Y. Rudy is the Fred Saigh Distinguished Professor at Washington University.

PII: S1547-5271(11)01133-7

doi: 10.1016/j.hrthm.2011.09.066

Heart Rhythm
Volume 9, Issue 2 , Pages 275-282 , February 2012

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