Advances in cardiac care of the young have given rise to a growing and aging population
of patients with congenital heart disease. Despite remarkable improvements in overall
survival, sudden cardiac death remains the most common cause of late mortality. As
a result, implantable cardioverter-defibrillators (ICDs) are increasingly used in
this heterogeneous patient population. Tetralogy of Fallot and transposition of the
great arteries are the most prevalent subtypes of congenital heart disease in ICD
recipients.
1
,
2
,
3
Common to this young population is the high rate of lead-related complications and
inappropriate shocks.
1
,
2
,
3
In a multicenter study of patients with tetralogy of Fallot, 25% received inappropriate
shocks, predominantly due to sinus or supraventricular tachycardia.
1
Although a similar proportion of patients with transposition received inappropriate
shocks (24%), 62% were due to oversensing or lead dysfunction.
3
Herein, we offer 10 practical tips for optimizing ICD programming in patients with
congenital heart disease (Table 1) in view of reducing inappropriate and potentially avoidable shocks.
Table 1ICD programming tips for patients with congenital heart disease
Programming tip | Comment |
---|---|
Program faster VT detection rate | For example, 200 bpm for primary prevention; 30–60 ms slower than clinical or induced VT for secondary prevention |
Program monitoring zone | Should not interact with active zones in modern ICDs |
Program longer detection times | For example, 24 of 32 or 30 of 40 intervals |
Program fast VT zone | Allows use of ATP |
Program discriminators | For rates up to 200 bpm; “off” if complete AV block |
Deactivate rate smoothing | Except for VT triggered by short–long–short sequences |
Deactivate “safety” timers | “High rate time out” and “sustained rate duration” |
Program ATP in VF zone | If programmable, two sequences are superior to one |
Optimize number of ATP sequences | For example, at least 2 in faster VT zone, 4–6 in slower VT zone; burst not ramp |
Program maximum shock output | Recommended pending further data |
ATP = antitachycardia pacing; ICD = implantable cardioverter-defibrillator; VF = ventricular
fibrillation; VT = ventricular tachycardia.
Keywords
Abbreviations:
ATP (antitachycardia pacing), ICD (implantable cardioverter-defibrillator), SVT (supraventricular tachycardia), VF (ventricular fibrillation), VT (ventricular tachycardia)To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Heart RhythmAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Implantable cardioverter-defibrillators in tetralogy of Fallot.Circulation. 2008; 117: 363-370
- Results of a multicenter retrospective implantable cardioverter-defibrillator registry of pediatric and congenital heart disease patients.J Am Coll Cardiol. 2008; 51: 1685-1691
- Sudden death and defibrillators in transposition of the great arteries with intra-atrial baffles: a multicenter study.Circ Arrhythm Electrophysiol. 2008; 1: 250-257
- Differences in tachyarrhythmia detection and implantable cardioverter defibrillator therapy by primary or secondary prevention indication in cardiac resynchronization therapy patients.J Cardiovasc Electrophysiol. 2004; 15: 1002-1009
- Shock reduction using antitachycardia pacing for spontaneous rapid ventricular tachycardia in patients with coronary artery disease.Circulation. 2001; 104: 796-801
- Prospective randomized multicenter trial of empirical antitachycardia pacing versus shocks for spontaneous rapid ventricular tachycardia in patients with implantable cardioverter-defibrillators: Pacing Fast Ventricular Tachycardia Reduces Shock Therapies (PainFREE Rx II) trial results.Circulation. 2004; 110: 2591-2596
- A comparison of empiric to physician-tailored programming of implantable cardioverter-defibrillators: results from the prospective randomized multicenter EMPIRIC trial.J Am Coll Cardiol. 2006; 48: 330-339
- Strategic programming of detection and therapy parameters in implantable cardioverter-defibrillators reduces shocks in primary prevention patients: results from the PREPARE (Primary Prevention Parameters Evaluation) study.J Am Coll Cardiol. 2008; 52: 541-550
- Enhanced detection criteria in implantable defibrillators.J Cardiovasc Electrophysiol. 1998; 9: 261-268
- Optimal combination of discriminators for differentiating ventricular from supraventricular tachycardia by dual-chamber defibrillators.J Cardiovasc Electrophysiol. 2005; 16: 732-739
- Randomized controlled study of detection enhancements versus rate-only detection to prevent inappropriate therapy in a dual-chamber implantable cardioverter-defibrillator.Heart Rhythm. 2004; 1: 540-547
- Prevention of ventricular arrhythmias in the congenital long QT syndrome.Curr Cardiol Rep. 2000; 2: 492-497
- Absent ventricular tachycardia detection in a biventricular implantable cardioverter-defibrillator due to intradevice interaction with a rate smoothing pacing algorithm.Heart Rhythm. 2004; 1: 728-731
- Effects of a rate smoothing algorithm for prevention of ventricular arrhythmias: results of the Ventricular Arrhythmia Suppression Trial (VAST).Heart Rhythm. 2006; 3: 573-580
- Discriminatory therapy for very fast ventricular tachycardia in patients with implantable cardioverter defibrillators.Pacing Clin Electrophysiol. 2008; 31: 1095-1099
- Randomized, prospective comparison of four burst pacing algorithms for spontaneous ventricular tachycardia.Am J Cardiol. 1998; 82: 1422-1425
- Antitachycardia pacing in patients with implantable cardioverter defibrillators: how many attempts are useful?.Pacing Clin Electrophysiol. 1997; 20: 198-202
Article info
Publication history
Published online: November 08, 2010
Accepted:
October 30,
2010
Received:
September 6,
2010
Footnotes
This work was supported in part by the Canada Research Chair in Electrophysiology and Adult Congenital Heart Disease (PK). Dr. Mansour has served as a consultant for Biotronik.
Identification
Copyright
© 2011 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.