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To the Editor—Investigating sinoatrial node activation during sinus rhythm using phase mapping

Published:October 19, 2020DOI:https://doi.org/10.1016/j.hrthm.2020.09.023
      With great interest, we read the article by Parameswaran et al
      • Parameswaran R.
      • Lee G.
      • Morris G.M.
      • et al.
      Simultaneous epicardial-endocardial mapping of the sinus node in humans with structural heart disease: impact of overdrive suppression on sinoatrial exits.
      on the effect of overdrive suppression on sinoatrial exits. In this study, an important attempt was made to obtain a 3-dimensional view on sinoatrial node (SAN) activity from an endo-epicardial perspective. However, some important limitations of the mapping technique should be taken into account when interpreting the study results.
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      References

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        • Lee G.
        • Morris G.M.
        • et al.
        Simultaneous epicardial-endocardial mapping of the sinus node in humans with structural heart disease: impact of overdrive suppression on sinoatrial exits.
        Heart Rhythm. 2020; 17: 2154-2163
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        Direct proof of endo-epicardial asynchrony of the atrial wall during atrial fibrillation in humans.
        Circ Arrhythm Electrophysiol. 2016; 9e003648
        • Fedorov V.V.
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        • Chang R.
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        Optical mapping of the isolated coronary-perfused human sinus node.
        J Am Coll Cardiol. 2010; 56: 1386-1394

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