Marijuana and electronic cigarettes on cardiac arrhythmias

  • Robert A. Kloner
    Address reprint requests and correspondence: Dr Robert A. Kloner, Huntington Medical Research Institutes, 686 South Fair Oaks Avenue, Pasadena, CA 91105.
    Huntington Medical Research Institutes, Pasadena, California

    Keck School of Medicine at University of Southern California, Los Angeles, California
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Published:November 14, 2022DOI:
      Marijuana use has continued to increase since the legalization of the substance by many states. It is estimated that by the end of 2022, 52 million Americans will have used marijuana. As of August 2022, 38 states either decriminalized cannabis or authorized its use for medical or recreational adult use. Physicians must become aware of not only potential medical benefits but also potential medical dangers of this substance. Potential benefits, including those of synthetic cannabinoids, include reduction of severe nausea and vomiting related to cancer chemotherapy, improvements in certain types of pain, reduction in seizures in certain syndromes of young children, reduction of anorexia in adult patients with AIDS, and reduction of spasticity associated with multiple sclerosis. There are no well-established and clinically accepted benefits of marijuana on the cardiovascular system, although some studies suggest possible benefits in heart failure and preclinical studies suggest a reduction of ischemia/reperfusion injury.
      • Page R.L.
      • Allen L.A.
      • Kloner R.A.
      • et al.
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