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Editorial Commentary| Volume 20, ISSUE 3, P352-353, March 2023

Tissue repair after pulsed field ablation

  • Yoshifusa Aizawa
    Correspondence
    Address reprint requests and correspondence: Dr Yoshifusa Aizawa, Department of Research Development, Tachikawa Medical Center, 1-24, Asahioka, Nagaoka 940-8621, Japan.
    Affiliations
    Department of Research Development, Tachikawa Medical Center, Nagaoka, Japan
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Published:December 01, 2022DOI:https://doi.org/10.1016/j.hrthm.2022.11.022
      Catheter ablation is a well-established interventional approach for treating symptomatic drug-refractory paroxysmal atrial filtration (AF) with a class I, level A guideline.
      • Calkins H.
      • Hindricks G.
      • Cappato R.
      • et al.
      HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation.
      Conventional thermal-based methods, radiofrequency ablation (RFA) and cryoablation, irreversibly damage the myocardium from protein denaturation and tissue coagulation to obtain durable ablation and are associated with complications that facilitate the development of a new methodology of nonthermal AF ablation.
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      Linked Article

      • Ultra-microhistological study of nonthermal irreversible electroporation on the esophagus
        Heart RhythmVol. 20Issue 3
        • Preview
          Esophageal ulceration and even fistula are severe complications of pulmonary vein isolation using traditional thermal ablation. Nonthermal irreversible electroporation (NTIRE) is a new technique for pulmonary vein isolation in patients with atrial fibrillation. NTIRE has been shown to be a safe method for pulsed electroporation near the esophagus. NTIRE preserves the structural framework of the esophagus and allows for rapid recovery of the whole layers of the esophagus.
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