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Incidence of Infranodal Conduction Delay in Patients with Left Bundle Branch Block after Transcatheter Aortic Valve Replacement: Impact of the 2021 ESC Guidelines for Cardiac Pacing

  • Author Footnotes
    ∗ Both authors contributed equally and should be considered shared first authors.
    Patrick Badertscher
    Footnotes
    ∗ Both authors contributed equally and should be considered shared first authors.
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
    Search for articles by this author
  • Author Footnotes
    ∗ Both authors contributed equally and should be considered shared first authors.
    Nina Mäder
    Footnotes
    ∗ Both authors contributed equally and should be considered shared first authors.
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
    Search for articles by this author
  • Teodor Serban
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Thomas Nestelberger
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Gregor Leibundgut
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Christoph Kaiser
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Stefan Osswald
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Christian Sticherling
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
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  • Author Footnotes
    # Both authors contributed equally and should be considered shared last authors
    Sven Knecht
    Footnotes
    # Both authors contributed equally and should be considered shared last authors
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
    Search for articles by this author
  • Author Footnotes
    # Both authors contributed equally and should be considered shared last authors
    Michael Kühne
    Correspondence
    Corresponding author: Michael Kühne, MD, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland,
    Footnotes
    # Both authors contributed equally and should be considered shared last authors
    Affiliations
    Department of Cardiology, University Hospital Basel, Basel, Switzerland

    Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland
    Search for articles by this author
  • Author Footnotes
    ∗ Both authors contributed equally and should be considered shared first authors.
    # Both authors contributed equally and should be considered shared last authors
Published:January 21, 2023DOI:https://doi.org/10.1016/j.hrthm.2023.01.019
Incidence of Infranodal Conduction Delay in Patients with Left Bundle Branch Block after Transcatheter Aortic Valve Replacement: Impact of the 2021 ESC Guidelines for Cardiac Pacing
Previous ArticlemiR-448 regulates potassium voltage-gated channel subfamily A member 4 (KCNA4) in ischemia and heart failure
Next ArticleA supraventricular tachycardia and the response to para-Hisian pacing: What is the mechanism?
      The occurrence of left bundle branch block (LBBB) after transcatheter aortic valve replacement (TAVR) remains the most frequent complication of the procedure.
      • Khatri P.J.
      • Webb J.G.
      • Rodés-Cabau J.
      • et al.
      Adverse effects associated with transcatheter aortic valve implantation: A meta-analysis of contemporary studies.
      Ann Intern Med. 2013; 158: 35-46
      ,
      • Badertscher P.
      • Knecht S.
      • Zeljković I.
      • et al.
      Management of conduction disorders after transcatheter aortic valve implantation: results of the EHRA survey.
      EP Europace. 2022;
      Electrophysiological (EP) testing is recommended with a IIa indication in the new 2021 ESC-guidelines for cardiac pacing

      Glikson M, Nielsen JC, Kronborg MB et al. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J. 2021; 42:3427–3520.

      in patients with new LBBB with QRS ≥ 150ms or PR ≥ 240ms or with pre-existing LBBB with a delta of QRS/PR intervals of ≥ 20ms after TAVR. A cut-off for the HV interval ≥ 70 ms to consider PM implantation was suggested. However, evidence for these proposed cutoffs of the HV interval, QRS duration and PR interval is scarce in LBBB patients after TAVR.
      • Jørgensen T.H.
      • de Backer O.
      • Gerds T.A.
      • et al.
      Immediate Post-Procedural 12-Lead Electrocardiography as Predictor of Late Conduction Defects After Transcatheter Aortic Valve Replacement.
      JACC Cardiovasc Interv. 2018; 11: 1509-1518

      Keywords

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      References

        • Khatri P.J.
        • Webb J.G.
        • Rodés-Cabau J.
        • et al.
        Adverse effects associated with transcatheter aortic valve implantation: A meta-analysis of contemporary studies.
        Ann Intern Med. 2013; 158: 35-46
        View in Article
        • Badertscher P.
        • Knecht S.
        • Zeljković I.
        • et al.
        Management of conduction disorders after transcatheter aortic valve implantation: results of the EHRA survey.
        EP Europace. 2022;
        View in Article

      3. Glikson M, Nielsen JC, Kronborg MB et al. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J. 2021; 42:3427–3520.

        View in Article
        • Jørgensen T.H.
        • de Backer O.
        • Gerds T.A.
        • et al.
        Immediate Post-Procedural 12-Lead Electrocardiography as Predictor of Late Conduction Defects After Transcatheter Aortic Valve Replacement.
        JACC Cardiovasc Interv. 2018; 11: 1509-1518
        View in Article

      Article info

      Publication history

      Accepted: January 14, 2023
      Received in revised form: December 30, 2022
      Received: November 21, 2022

      Publication stage

      In Press Journal Pre-Proof

      Footnotes

      Funding: None.

      Disclosures

      Patrick Badertscher has received research funding from the “University of Basel“, the “Stiftung für Herzschrittmacher und Elektrophysiologie”, the “Freiwillige Akademische Gesellschaft Basel” and Johnson&Johnson, all outside the submitted work.

      Sven Knecht has received funding of the “Stiftung für Herzschrittmacher und Elektrophysiologie” .

      Christian Sticherling: Member of Medtronic Advisory Board Europe and Boston Scientitic Advisory Board Europe, received educational grants from Biosense Webster and Biotronik and a research grant from the European Union’s FP7 program and Biosense Webster and lecture and consulting fees from Abbott, Medtronic, Biosense-Webster, Boston Scientific, Microport, and Biotronik all outside the submitted work

      Michael Kühne reports personal fees from Bayer, personal fees from Böhringer Ingelheim, personal fees from Pfizer BMS, personal fees from Daiichi Sankyo, personal fees from Medtronic, personal fees from Biotronik, personal fees from Boston Scientific, personal fees from Johnson&Johnson, personal fees from Roche, grants from Bayer, grants from Pfizer, grants from Boston Scientific, grants from BMS, grants from Biotronik, grants from Daiichi Sankyo, all outside the submitted work.

      Others have nothing to declare.

      Identification

      DOI: https://doi.org/10.1016/j.hrthm.2023.01.019

      Copyright

      © 2023 Published by Elsevier Inc. on behalf of Heart Rhythm Society.

      ScienceDirect

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