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Editorial Commentary|Articles in Press

Mortality of ablation of atrial fibrillation: 25 Years later, still too risky for too many

      On this year’s 25th anniversary of the landmark report
      • Haissaguerre M.
      • Jaïs P.
      • Shah D.C.
      • et al.
      Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins.
      on ablation of pulmonary vein ectopy initiating atrial fibrillation (AF), which preceded by 1 year ablation of AF using nonfluoroscopic 3-dimensional mapping,
      • Pappone C.
      • Oreto G.
      • Lamberti F.
      • et al.
      Catheter ablation of paroxysmal atrial fibrillation using a 3D mapping system.
      we are reminded how both approaches would forever transform cardiac electrophysiology as a predominant diagnostic discipline, also performing device implantation and ablation of supraventricular tachycardia to become a therapeutic catheter ablation interventional specialty. Clinical cardiac electrophysiologists were somewhat unprepared or caught off guard a few years later when atrioesophageal fistulas, associated with significant morbidity and mortality, were first reported as a complication of ablation of AF.
      • Pappone C.
      • Oral H.
      • Santinelli V.
      • et al.
      Atrial-esophageal fistula as a complication of percutaneous transcatheter ablation of atrial fibrillation.
      During an era of debates on ventricular rate control or maintenance of sinus rhythm strategies to treat patients with AF, complications of ablation of AF significantly influenced the development of mapping and energy delivery technologies.
      • Cappato R.
      • Calkins H.
      • Chen S.A.
      • et al.
      A worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation.
      ,
      • Calkins H.
      • Brugada J.
      • Packer D.L.
      • et al.
      European Heart Rhythm Association (EHRA); European Cardiac Arrhythmia Society (ECAS); American College of Cardiology (ACC); American Heart Association (AHA); Society of Thoracic Surgeons (STS)
      HRS/EHRA/ECAS Expert Consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for personnel, policy, procedures and follow-up. A report of the Heart Rhythm Society (HRS) Task Force on catheter and surgical ablation of atrial fibrillation.
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