Sustained ventricular arrhythmias (VAs) are a leading cause of morbidity and mortality
worldwide.
1
The autonomic nervous system has been recognized as an important modulator of sustained
VAs and electrical storm (defined as ≥3 sustained VAs within a 24-hour period).
1
,2
Percutaneous stellate ganglion (SG) blockade has emerged as an alternative and effective
modality for managing patients with hemodynamically unstable refractory VAs or electrical
storm.
2
,
3
,
4
To date, literature on the efficacy and safety profile of SG blockade has been limited
to case reports and small cohort studies. It is in this context that Lador et al
5
sought to further investigate the utility of SG instrumentation in the management
of sustained VAs.To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Heart RhythmAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Europace. 2019; 21: 1143-1144
- Effective use of percutaneous stellate ganglion blockade in patients with electrical storm.Circ Arrhythm Electrophysiol. 2019; 12e007118
- Stellate ganglion blockade for the treatment of refractory ventricular arrhythmias: a systematic review and meta-analysis.J Cardiovasc Electrophysiol. 2017; 28: 1460-1467
- Stellate ganglion blockade for the treatment of refractory ventricular arrhythmias.JACC Clin Electrophysiol. 2020; 6: 562-571
- Stellate ganglion instrumentation for pharmacological blockade, nerve recording and stimulation in patients with ventricular arrhythmias: preliminary experience.Heart Rhythm. 2023; (XX:XX–XX)
- Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death.Heart Rhythm. 2008; 5: 131-139
- Augmentation of cardiac sympathetic tone by percutaneous low-level stellate ganglion stimulation in humans: a feasibility study.Physiol Rep. 2015; 3e12328
- Effects of stepwise denervation of the stellate ganglion: novel insights from an acute canine study.Heart Rhythm. 2016; 13: 1395-1401
Article info
Publication history
Published online: March 07, 2023
Publication stage
In Press Journal Pre-ProofFootnotes
Funding Sources: The authors have no funding sources to disclose.
Disclosures: The authors have no conflicts of interest to disclose.
Identification
Copyright
© 2023 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.
