Dodeja et al (Pediatr Cardiol February 10, 2023; https://doi.org/10.1007/s00246-023-03120-1, PMID 36763139) reported the results of their single-center retrospective study on
ventricular arrhythmia (VA)–specific outcomes after transcatheter pulmonary valve
replacement (TPVR). The 81 included patients were all older than 18 years and underwent
TPVR between 2010 and 2019 at a mean age of 27 ± 13 years. Mean follow-up was 6.4
± 3 years. VAs occurred in 4 patients (5%). A variety of clinical risk factors were
compared between those with VAs and those without, including ventricular function,
surgical era, history of ventriculotomy, history of palliative shunt, history of arrhythmia,
QRS duration, QRS fragmentation, and left ventricular end-diastolic pressure when
available. There was no difference in any risk factors between groups. Patients deemed
at a moderate risk of VA events before TPVR underwent an electrophysiology study (EPS)
for ventricular stimulation (n = 13), 4 of whom had a positive result. Of the 4 patients
with VA events, only 1 underwent an EPS, which was negative. The authors conclude that “current era” risk factors did not differentiate outcomes
after TPVR and that an evolving approach to risk assessment will be necessary as disease
factors evolve.
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Article info
Publication history
Published online: March 09, 2023
Publication stage
In Press Journal Pre-ProofFootnotes
Funding Sources: The author has no funding sources to disclose.
Disclosures: The author has no conflicts of interest to disclose.
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